Den of Geek
Perhaps the biggest difference between the book and TV version of The Handmaid's Tale is one of perspective. Unbound by the book's conceit (that the entire story is a transcription of audio tapes Offred recorded at an unclear point in time), the show follows storylines after they leave our narrator's purview. We are still in Offred's head much of the time, but our default is an observer of her and others' actions, rather than receiving information solely from her. It may not sound like much, but it's the difference between seeing her eyes and seeing through her eyes.