On The Last Ship Season 1 Episode 4, we were given a look non-human enemies through mechanical failures and weather that failed to cooperate.
It was a good perspective. It proves that there is more to propel the series forward other than the lure of the cure and bitter adversaries.
The ship itself suffers due to a lack of docking and refueling. The crew is tasked with keeping it afloat and protecting the cure with only the ingenuity of the sailors on board. As it turns out, it makes for a pretty compelling tale.