The CDC gets called in to investigate when Regis Flight 753 arrives in NYC as a "dead plane." The passengers deaths can't be attributed to any cause that they've seen before.
Eph Goodweather leads the team that examines the plane, passengers and is tasked with determining the cause. The mystery leads them to an ancient and evil strain of vampirism. It's scary, creepy, and intense!
The series has a wide-range of characters, including the CDC's Canary Project team, those involved in the spread of the outbreak, a former death camp prisoner who's dealt with an outbreak before and Eph's family members.