Jeremy of The Daily Rotation wrote, "Jeff, Who Lives at Home is the latest film from Jay and Mark Duplass; two filmmakers known primarily for their independent work. Their widest reached work is probably Cyrus. They’re mostly unknown to the mainstream audiences, but I think that’s all going to change. Jeff, Who Lives at Home is a film that gets you interested because of its comedy, but keeps you invested because of its connecting story that makes every single event in the film happen for a reason, a greater purpose. It hangs on the whole idea of destiny and it progressively changes every main character in the film, leaving you with an impressive film that works off of such a basic concept, expanding it into a performance driven dramedy."