CinemaBlend says
I remember it distinctly. It was the summer of 2004 and I was in Boston when a few friends and I headed to the movie theater to see the new stoner comedy Harold and Kumar Go To White Castle. Towards the middle of the film the duo pulls over to pick up a hitchhiker walking along the side of the road. The stranger gets into the backseat of the car, Harold and Kumar look at each other, and, almost in unison with Kal Penn, I whispered, "Is that Neil Patrick Harris?" Thus was born one of the greatest cameos of all time as the former Doogie Howser star proceeded to hump the driver's seat, steal the car and do coke off of some stripper's tits. In the year's since NPH has become a cultural icon, starring as Barney Stinson on the hit show How I Met Your Mother, starring in multiple films, hosting both the Tony and Emmy awards, and reprising his role as "Neil Patrick Harris" in Harold and Kumar Escape From Guantanamo Bay. Now the third film in the franchise, A Very Harold and Kumar Christmas 3D, is set to arrive this winter and it would seem that the envelope is being pushed even further.
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NPH is absolutely hilarious in these movies. I'm looking forward to this movie big time.