CinemaBlend:
You’re in here to learn iron clad news about Monsters Inc. 2, but you need to know right away that information like this does not yet exist. However, a site across the pond in France has spit some rhymes about Pixar’s next sequel.
The big rumor comes from French site Disney Central Plaza who has it that Monsters Inc. 2 won’t be a sequel at all, but a prequel.
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Nerd Reactor writes that a new international post has revealed the return of a fan-favorite Toho monster.
I could see it working in this instance. There wasn't a whole lot to work with at the end of Monster Inc. The only thing they could do in that regards is have an enemy or rival power company. Maybe bad guy monsters scaring children.