Director Vincenzo Natali has been, for the most part, an obscure filmmaker still best known for his first feature, CUBE, which came out all the way back in 1997. He's since directed Canadian t.v. ("Earth: Final Conflict"), and had a segment in the anthology PARIS , JE T'AIME, but is as far from a household name as you can get. That has the potential to change with SPLICE, a film that Natali made last year (with producer Guillermo del Toro) that went on to make a big splash at Sundance and subsequently get picked up by Joel Silver's Dark Castle and Warner Bros. Pictures. It's opening in wide release on June 4th.